Serena returned from a maternity break to lose 6-2, 3-6, 10-5 to the 20-year-old Latvian.
Sofia Kenin said that the experience at Roland Garros changed her career trajectory.
Serena Williams crashed out of the US Open after losing in the semi-final to Karolina Pliskova costing her a shot at a 23rd Grand Slam title and resulted in her losing her record 187th straight week at number one.
If Serena Williams' rivals were hoping that the American would take some time out to savour drawing level with Steffi Graf's professional-era record of 22 grand slam titles, her coach Patrick Mouratoglou fired off an immediate warning.
Serena Williams said the work is never done for mothers who are also professional tennis players following her victory over fellow mom Tsvetana Pironkova in the US Open quarter-finals on Wednesday.
Maria Sharapova and world No 1 Serena Williams haven't played each other at the Wimbledon Championships since their Round of 16 clash in 2010.
Serena said she felt 'pretty fresh' ahead of the claycourt swing as she prepares for the French Open
There were no wild celebrations or fist pumps from Serena Williams after she beat Caroline Wozniacki at the WTA Finals on Saturday.
A factfile on Serena Williams's controversial moments with officials at the US Open following her defeat to Japan's Naomi Osaka in Saturday's final.
World number one Serena Williams slammed Shamil Tarpishchev for using "extremely sexist, racist and bullying" comments after the Russian Tennis Federation (RTF) president described her and sister Venus as the "Williams brothers".
'I'm not thinking ahead to the Open right now because I am here in Toronto and I haven't really played a hard court match in awhile. I'm thinking I want to get some of this under my belt and the Open will happen when the Open happens.'
World number one Serena Williams was ruled out of her opening match at the Hopman Cup mixed team event in Perth on Monday because of inflammation of the knee, organisers said.
Serena and Olympia look glamorous in hot pink dresses from the legendary fashion house Balmain.
SSerena Williams swept past Anastasija Sevastova 6-3, 6-0 on Thursday and into the final of the US Open to sit one win away from a record-equalling 24th Grand Slam title.
Williams has just one professional tournament remaining before she drops the curtain on her historic career
'I'm terrible at goodbyes, the world's worst'
Reader Girish sent us these pictures from Bangalore.
The duo hailed each other in the post-match interview before the tennis titans captured the iconic moment in what Hopman Cup on Twitter described as the 'greatest selfie of all time'.
Wimbledon was scrapped for the first time since World War Two on Wednesday due to the coronavirus pandemic, with the suspension of professional tennis extended to July 13. The 38-year-old Federer is well insulated from the shutdown's financial fallout it could well impact his hopes of adding to his record haul of 20 Grand Slam titles.
Such has been Serena Williams's iron-fisted dominance of women's tennis that the American is one Wimbledon title away from achieving a 'Serena Slam' and halfway towards completing a rare calendar Grand Slam.
Serena Williams claimed a sixth Wimbledon title and fourth successive Grand Slam crown by suppressing the spirited attacking instincts of 20th-seeded Spaniard Garbine Muguruza to win Saturday's final 6-4, 6-4.
Sinner's settlement brought plenty of criticism from both current and former players, with Serena Williams saying she would have been banned for 20 years and had her Grand Slam titles taken away had she tested positive in a similar fashion.
World number one Serena Williams survived a mid-match meltdown to beat Czech Lucie Safarova 6-3, 6-7(2), 6-2 to win the French Open on Saturday, her 20th Grand Slam singles trophy.
Serena has remained one title behind Margaret Court's all-time record since bagging her 23rd Grand Slam singles trophy
Twitter lit up with reactions after Naomi Osaka defeated the American in a stormy final on Saturday:
It will be the 22nd career match-up between the two long-time rivals, who somehow have avoided each other at the US Open throughout their long careers.
Australian newspaper defies criticism, reprints Serena Williams cartoon
Following her US Open quarter-final win over elder sister Venus, the 21-year-old tennis player said that she did not want to answer any media queries, according to E! Online.
The shock losses suffered by top two seeds Serena Williams and Li Na have left Maria Sharapova with a smooth passage and the Russian is primed to win her second Wimbledon title, 10 years after winning her first as a 17-year-old.
Tennis star Serena Williams says she is concerned about the Zika outbreak ahead of August's Rio Olympics, but has faith in the support team dealing with worries about the mosquito-carried virus.
Serena Williams was completely taken aback by her pregnancy, taking six home tests before believing she was expecting her first child, the tennis superstar told Vanity Fair magazine.
Serena Williams took the first cautious step towards a record-equalling 24th Grand Slam title with a 6-4, 6-0 first-round win over Magda Linette.
Frenchman Mouratoglou said Williams had been able to recharge during the break and that her appetite for titles had not waned.
Serena Williams' memory is not as powerful as her first serve these days, although with so many achievements to recall it would be churlish to hold that against the American great.
The unseeded Bencic, who also beat former world number ones Caroline Wozniacki and Ana Ivanovic in Toronto, wore a look of disbelief after the 18-year-old's forehand winner whizzed past Williams to seal the match.
Serena Williams was forced to dig deep to secure a 4-6, 6-3, 6-2 US Open quarter-final victory over unseeded Bulgarian Tsvetana Pironkova on Wednesday, keeping alive her latest bid for a record-tying 24th Grand Slam singles title.
For the second straight year Serena Williams saw her bid for a seventh U.S. Open title halted in the semi-finals with a 6-2 7-6(5) loss to Karolina Pliskova on Thursday that also ended her long reign as world number one.
Trump's return to the US Open bore an uncanny resemblance to his last trip. In 2015, Trump was booed after leaving a match between the Williams sisters, Serena and Venus.
With a 6-2, 6-1 3rd round win over Swedish Johanna Larsson at the US Open at Flushing Meadows on Saturday, Serena recorded her 307th Grand Slam victory and in doing so went past legendary Martina Novratilova to record the most wins in a major by a woman.
'She wants to come back in 2018 and defend her title and she's in training now'